| K | Kelvin |
| K | kilocycle |
| K | thousand |
| K-APM | KSC automated payloads plan/requirement |
| K-APN | KSC automated payloads notice |
| K-APPS | KSC automated payloads project specification |
| K-CITEM | KSC CITE plan/requirement |
| K-DODM | KSC DOD plan/requirement |
| K-DPM | KSC DOD payloads plan/requirement |
| K-DPN | KSC DOD payloads notice |
| K-DPPS | KSC DOD payloads project specification |
| K-IUSM | KSC IUS plan/requirement |
| K-IUSN | KSC IUS notice |
| K-IUSPS | KSC IUS project specification |
| K-MMSEM | KSC MMSE plan/requirement |
| K-MMSEN | KSC MMSE notice |
| K-MMSEPS | KSC MMSE project specification |
| K-SLM | KSC Spacelab plan/requirement |
| K-SLN | KSC Spacelab notice |
| K-SLPS | KSC Spacelab project specification |
| K-SM | KSC Shuttle management document |
| K-SPN | KSC Shuttle project notice |
| K-SPS | KSC Shuttle project specification |
| K-SSS | KSC Shuttle project station set specification |
| K-STSM | KSC STS plan/requirement |
| K-STSN | KSC STS notice |
| K-STSPS | KSC STS project specification |
| K-load | constant load |
| K/S | kick stage |
| KA | kill assessment |
| KAPL | KSC approved parts list |
| KATE | knowledge-based autonomous test engineer |
| KATS | KSC avionics test set |
| KAU | kilo accounting unit |
| KB | keyboard |
| KBAC | Kennedy booster assembly contractor |
| KBC | Kapton beta cloth |
| KBIM | keyboard interface module |
| KBS | knowledge-based system |
| KBSA | knowledge-based software assistant |
| KBU | keyboard unit |
| KCAS | knots calibrated airspeed |
| KCR | KSC change request |
| KCRT | keyboard cathode-ray tube |
| KCS | key configuration study |
| KCS | keyboard configuration study |
| KCV | KKV carrier vehicle |
| KDMS | Kennedy data management system |
| KDN | kinetically designed nozzle |
| KDS | Kennedy-developed software |
| KDT | keyboard and display test |
| KDV | KKV deployment vehicle |
| KE | kinetic energy |
| KEAS | knots equivalent airspeed |
| KEE | knowledge engineering environment |
| KELV | KKV/ESM launch vehicle |
| KEV | kinetic-energy vehicle |
| KEW | kinetic-energy weapon |
| KHB | KSC Handbook |
| KHIL | KKV hardware in the loop |
| KHILS | KKV hardware-in-the-loop simulator |
| KHIT | KKV hovering interceptor test |
| KIAS | knots indicated airspeed |
| KIMS | KSC inventory management system |
| KIP | keyboard input processor |
| KIS | kitting instruction sheet |
| KKV | kinetic kill vehicle |
| KKVWS | kinetic kill vehicle weapon system |
| KKW | kinetic kill weapon |
| KMI | KSC management instruction |
| KMR | Kwajalein Missile Range |
| KMR | key milestone review |
| KN | KSC notice |
| KN | kitting notice |
| KNO | Kano, Nigeria |
| KOH | potassium hydroxide |
| KOI | KSC operation instruction |
| KOM | KSC organizational manual |
| KOSC | Kennedy Operations Support Center |
| KPD | KSC program directive |
| KPRD | KSC program requirements document |
| KPSM | Klystron power supply modulator |
| KREMS | Kiernan reentry measurements site |
| KREMS | Kwajalein reentry measurement system |
| KSA | Ku-band single access |
| KSC | Kennedy Space Center |
| KSCAP | Kennedy Space Center area permit |
| KSLOC | thousands of source lines of code |
| KSSS | KSC station set specification |
| KTF | Kauai Test Facility |
| KU | keyboard unit |
| KV | kill vehicle |
| KuSP | Ku-band signal processor |
| k | kilo- (thousand) |
| kHz | kilohertz |
| kV | kilovolt |
| kVA | kilovolt-ampere |
| kW | kilowatt |
| kWh | kilowatt-hour |
| kb | kilobit |
| kbps | kilobits per second |
| kbs | kilobits per second |
| keV | kiloelectron volt |
| kg | kilogram |
| kgal/min | kilogallons per minute |
| klb | thousands of pounds (kilopounds) |
| km | kilometer |
| km/hr | kilometers per hour |
| kops | thousands of operations per second |
| kpps | kilopulses per second |
| kps | kilometers per second |
| krem | kilorem |
| ks/s | kilosymbols per second |